UTI, prophylaxis
|
Some Antimicrobials for Prophylaxis of UTI |
|
| Antimicrobial | Dosage |
| TMP in combination with SMX | 2 mg of TMP, 10 mg of SMX per kg as single bedtime dose or 5 mg of TMP, 25 mg of SMX per kg twice per week. Avoid in infants < 3 mos of age and G6PD deficiency |
| Nitrofurantoin | 1-2 mg/kg as single daily dose. Avoid in infants < 3 mos of age, G6PD deficiency, renal insufficiency. Causes gastrointestinal upset |
| Sulfisoxazole | 10-20 mg/kg divided every 12 h |
| Nalidixic acid | 30 mg/kg divided every 12 h |
| Methenamine mandelate | 75 mg/kg divided every 12 h |
| Cephalexin | 10 mg/kg/day. Drug of choice in first 3-6 mos of life |