McCune-Albright
-
Fibrous dysplasia
- irregular brown pigmentation
- Coast of Maine cafe-au-lait spot
(irregular border vs NF-1 - smooth border "coast of california"
- follows lines of
Blaschko (pathways of embronal cell migration, occurs
along skin folds)
- often end abruptly at midline except in lower back
- endocrine
- precocious puberty
- hyperthyroidism
- hyperparathyroidism
- acromegaly
- Cushing's
- hyperprolactin
2005 CHLA board review