also Complications of chemo: general

  1. LCH (EHL) Dave 'Birbeck' on CD1a: bone pain, rash, draining ear, draining pee, bumps, pallor/bleed, pulmonary infiltrates
  3. malignant

Class I- Langerhan Cell Histiocytosis

Class II- Hemophagocytic LymphoHistiocytosis (HLH)

Class III- Malignant form - true malignancy of monocyte-macrophage lineage

Now, it is important to note that this class of disease is rare, but should be kept in the back of our minds when we see a painful bony lesion (it's one of the 3 classic nonosseous tumors that we must consider in evaluation of bone pain, along with Neuroblastoma and Leukemia) or chronic constitutional symptoms like weight loss, irritability, fatigue.....

Also see Wiscott Aldritch, other skin stuff