Coloboma (always refer to optho because may have coloboma of retina)
Heart disease: TOF/VSD/PDA
Retarded growth/development/CNS anomalies
Genital anomalies or hypogonadism
Ear anomalies or deafness
CHARGE association is characterized by Coloboma, Heart defects, Atresia choanae, Retarded growth, central nervous system anomalies, Genital anomalies, and Ear abnormalities. Although features of both Noonan Syndrome and Turner syndrome can include a low hairline and short neck, neither is associated with fused vertebrae or facial asymmetry. Infants who have trisomy 13 present in the newborn period with defects of the forebrain, which can include holoprosencephaly, microcephaly, polydactyly, and clefting.